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ARSENIC


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Health concerns of ingredient
About the ratings
Canceryes
Developmental & reproductive toxicityyes
Allergies & immunotoxicityyes
Other HIGH concerns: Organ system toxicity (non-reproductive), Occupational hazards, Use restrictions
Other MODERATE concerns: Neurotoxicity, Endocrine disruption, Persistence and bioaccumulation
Other LOW concerns: Ecotoxicology, Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Synonym(s): ARSENIC, DISSOLVED; ARSENIC (INORGANIC ONLY) ; ARSENIC (TOTAL) ; AS; ARSEN (GERMAN,POLISH) ; ARSENIC (ACGIH:OSHA) ; ARSENIC BLACK; ARSENIC, ELEMENTAL; ARSENIC-75; ARSENICALS; COLLOIDAL ARSENIC

Cancer

Type of Concern Reference
Known human carcinogenAmer Conf of Gov't Industrial Hygienists - Carcinogens
Known human carcinogenEPA Integrated Risk Information System (IRIS)
Known human carcinogenInt'l Agency for Research on Cancer (IARC) - Carcinogens
Known human carcinogenNTP Report on Carcinogens, 11th Edition
Possible human carcinogenCalifornia EPA Proposition 65
Cancer - moderate evidence - hematologicCHE Toxicant and Disease Database
Cancer - moderate evidence - gastrointestinalCHE Toxicant and Disease Database
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Allergies/immunotoxicity

Type of Concern Reference
Human skin toxicant - strong evidenceCHE Toxicant and Disease Database
Human skin and immune toxicant - strong evidenceCHE Toxicant and Disease Database
Human skin and immune toxicant - moderate evidenceCHE Toxicant and Disease Database
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Developmental/reproductive toxicity

Type of Concern Reference
Possible human developmental toxicantCalifornia EPA Proposition 65
Human developmental toxicant - moderate evidenceCHE Toxicant and Disease Database
Human nervous system toxicant - moderate evidenceCHE Toxicant and Disease Database
Human musculoskeletal toxicant - moderate evidenceCHE Toxicant and Disease Database
Human nervous system toxicant - moderate evidenceChemicals known to be neurotoxic to humans
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Neurotoxicity

Type of Concern Reference
Strong evidence of human neurotoxicityCHE Toxicant and Disease Database
Strong evidence of human neurotoxicityChemicals known to be neurotoxic to humans
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Endocrine disruption

Type of Concern Reference
Human endocrine disruptor - strong evidenceCHE Toxicant and Disease Database
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Organ system toxicity (non-reproductive)

Type of Concern Reference
Known human respiratory toxicantEPA Hazardous Air Pollutants
Known human cardiovascular toxicantCHE Toxicant and Disease Database
Known human sense organ toxicantCHE Toxicant and Disease Database
Known human skin toxicantCHE Toxicant and Disease Database
Possible human hematologic toxicantCHE Toxicant and Disease Database
Possible human respiratory toxicantCHE Toxicant and Disease Database
Possible human cardiovascular toxicantCHE Toxicant and Disease Database
Possible human gastrointestinal toxicantCHE Toxicant and Disease Database
Possible human sense organ toxicantCHE Toxicant and Disease Database
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Persistence and bioaccumulation

Type of Concern Reference
Persistent, bioaccumulative in wildlifeCanada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
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Occupational hazards

Type of Concern Reference
Allowed workplace exposures restricted to very low dosesNational Library of Medicine HazMap
Allowed workplace exposures restricted to low dosesEuropean Union - Classification & Labelling
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Ecotoxicology

Type of Concern Reference
Wildlife and environmental toxicityEuropean Union - Classification & Labelling
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Multiple, additive exposure sources

Type of Concern Reference
Designated as safe for general or specific, limited use in food FDA Food Additive Status

Data gaps

Type of Concern Reference
Not assessed for safety in cosmetics by industry panel

Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)

references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Amer Conf of Gov't Industrial Hygienists - CarcinogensACGIH (American Conference of Governmental Industrial Hygienists) 2008. ACGIH cancer classification system. www.acgih.org.
FDA Food Additive StatusFDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Association of Occupational and Environmental ClinicsAOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
Canada - Prohibited and Restricted Cosmetics IngredientsHealth Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
CHE Toxicant and Disease DatabaseCHE (The Collaborative on Health and the Environment). 2006. Toxicant and Disease Database.
EPA Clean Water Act - Priority Pollutants
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA Integrated Risk Information System (IRIS)EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
EPA Hazardous Air PollutantsEPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Int'l Agency for Research on Cancer (IARC) - CarcinogensIARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
Chemicals known to be neurotoxic to humansGrandjean P and PJ Landrigan. 2006. Developmental neurotoxicity of industrial chemicals. Lancet. 2006 Dec 16;368(9553):2167-78.
NTP Report on Carcinogens, 11th EditionNTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
Our Stolen Future Endocrine DisruptorsColborn T, D Dumanoski, JP Myers. 2006. Widespread Pollutants with Endocrine-disrupting Effects. Updated from original listing in "Our Stolen Future" (1996).
Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
California EPA Proposition 65California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.

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