1,2,4-TRIMETHYLBENZENE
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About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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Synonym(s): ASYMMETRICAL TRIMETHYLBENZENE; BENZENE, 1,2,5-TRIMETHYL-; PSEUDOCUMENE; PSEUDOCUMOL; AS-TRIMETHYLBENZENE; PSI-CUMENE
Occupational hazards |
| Type of Concern |
Reference |
|---|
| Allowed workplace exposures restricted to low doses | European Union - Classification & Labelling |
Irritation (skin, eyes, or lungs) |
| Type of Concern |
Reference |
|---|
| Classified as irritant | European Union - Classification & Labelling |
Organ system toxicity (non-reproductive) |
| Type of Concern |
Reference |
|---|
| Limited evidence of respiratory toxicity | |
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| Limited evidence of cardiovascular or blood toxicity | |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Toxic Release Inventory PBTs |
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List | |
Ecotoxicology |
| Type of Concern |
Reference |
|---|
| Wildlife and environmental toxicity | European Union - Classification & Labelling |
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| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List | |
Neurotoxicity |
| Type of Concern |
Reference |
|---|
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | National Library of Medicine HazMap |
Persistence and bioaccumulation |
| Type of Concern |
Reference |
|---|
| Not suspected to be persistent | Environment Canada Domestic Substance List |
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| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List | |
Miscellaneous |
| Type of Concern |
Reference |
|---|
| Occupational hazards related to handling |
European Union - Classification & Labelling |
Data gaps |
| Type of Concern |
Reference |
|---|
| Not assessed for safety in cosmetics by industry panel |
|
Government, industry, academic studies and classifications |
| government/industry list/academic study |
appears on list as |
classification(s) |
references |
| government/industry list/academic study
| reference
|
| European Union - Classification & Labelling | CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP. |
| Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| IFRA Fragrance Ingredient List | IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25 |
| National Library of Medicine HazMap | NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents. |
| EPA Toxic Release Inventory PBTs | EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule. |
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