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BUTADIENE


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Health concerns of ingredient
About the ratings
Canceryes
Developmental & reproductive toxicityyes
Allergies & immunotoxicity no information
Other HIGH concerns: Organ system toxicity (non-reproductive), Use restrictions
Other LOW concerns: Occupational hazards

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Synonym(s): 1,3-BUTADIENE (ACGIH:OSHA) ; BIETHYLENE; BIVINYL; BUTA-1,3-DIEEN (DUTCH) ; BUTA-1,3-DIEN (GERMAN) ; BUTA-1,3-DIENE; BUTADIEEN (DUTCH) ; BUTADIEN (POLISH) ; BUTADIENE (OSHA) ; BUTADIENE-1,3; DIVINYL

Cancer

Type of Concern Reference
Known human carcinogenEPA Integrated Risk Information System (IRIS)
Known human carcinogenInt'l Agency for Research on Cancer (IARC) - Carcinogens
Known human carcinogenNTP Report on Carcinogens, 11th Edition
Known human carcinogenEuropean Union - Classification & Labelling
Possible human carcinogenNTP - Tumor Induction in Mammary Gland
Cancer - strong evidence
Possible human carcinogenCalifornia EPA Proposition 65
Possible human carcinogenInt'l Agency for Research on Cancer (IARC) - Carcinogens
Possible human carcinogenAmer Conf of Gov't Industrial Hygienists - Carcinogens
Possible human carcinogenEuropean Union - Classification & Labelling
Limited evidence of carcinogenicityNIOSH Occupational Carcinogens
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Developmental/reproductive toxicity

Type of Concern Reference
Possible human developmental toxicantCalifornia EPA Proposition 65
Human developmental toxicant - strong evidence
Human reproductive toxicant - strong evidence
Limited evidence of reproductive toxicityNational Library of Medicine HazMap
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Organ system toxicity (non-reproductive)

Type of Concern Reference
Known human respiratory toxicantEPA Hazardous Air Pollutants
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Persistence and bioaccumulation

Type of Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
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Miscellaneous

Type of Concern Reference
Occupational hazards related to handling European Union - Classification & Labelling

Ecotoxicology

Type of Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Type of Concern Reference

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)

references
government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Amer Conf of Gov't Industrial Hygienists - CarcinogensACGIH (American Conference of Governmental Industrial Hygienists) 2008. ACGIH cancer classification system. www.acgih.org.
CHE Toxicant and Disease DatabaseCHE (The Collaborative on Health and the Environment). 2006. Toxicant and Disease Database.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA Integrated Risk Information System (IRIS)EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
European Union - Banned or Restricted in CosmeticsEC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation."
EPA Hazardous Air PollutantsEPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Int'l Agency for Research on Cancer (IARC) - CarcinogensIARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
NIOSH Occupational CarcinogensNIOSH (National Institute for Occupational Safety and Health). 2006. NIOSH Carcinogens List (Potential occupational carcinogens). http://www.cdc.gov/niosh/npotocca.html.
NTP Report on Carcinogens, 11th EditionNTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
NTP - Tumor Induction in Mammary GlandNTP (National Toxicology Program) 2006. Chemicals Associated with Site-Specific Tumor Induction in Mammary Gland.
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
California EPA Proposition 65California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
Silent Spring's Mammary Carcinogens Reviews DatabaseRudel RA, KR Attfield, JN Schifano and JG Brody. Chemicals Causing Mammary Gland Tumors in Animals Signal New Directions for Epidemiology, Chemicals Testing, and Risk Assessment for Breast Cancer Prevention. CANCER Supplement. 2007 Jun 15;109(12):2635-2666.

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