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BIPHENYL


image source: PubChem
Health concerns of ingredient
About the ratings
Canceryes
Developmental & reproductive toxicityyes
Allergies & immunotoxicity no information
Other HIGH concerns: Organ system toxicity (non-reproductive), Irritation (skin, eyes, or lungs)
Other LOW concerns: Ecotoxicology, Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Synonym(s): 1,1'-BIPHENYL; BIBENZENE; BIPHENYL (ACGIH:OSHA) ; CAROLID AL; CP 390; DIPHENYL (OSHA) ; LEMONENE; MCS 1572; PHENADOR-X; PHENYLBENZENE; PHPH

Organ system toxicity (non-reproductive)

Type of Concern Reference
Known human respiratory toxicantEPA Hazardous Air Pollutants
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Developmental/reproductive toxicity

Type of Concern Reference
Limited evidence of developmental toxicity

Cancer

Type of Concern Reference
Cancer - not classifiable/not likely to be human carcinogenEPA Integrated Risk Information System (IRIS)

Irritation (skin, eyes, or lungs)

Type of Concern Reference
Classified as irritantEuropean Union - Classification & Labelling

Ecotoxicology

Type of Concern Reference
Wildlife and environmental toxicityEuropean Union - Classification & Labelling
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Neurotoxicity

Type of Concern Reference
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Endocrine disruption

Type of Concern Reference
endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyOur Stolen Future Endocrine Disruptors

Persistence and bioaccumulation

Type of Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
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Multiple, additive exposure sources

Type of Concern Reference
Designated as safe for general or specific, limited use in food FDA Everything Added to Food

Data gaps

Type of Concern Reference
Not assessed for safety in cosmetics by industry panel
Insufficient data to determine safety EPA Integrated Risk Information System (IRIS)

Government, industry, academic studies and classifications

government/industry list/academic study appears on list as classification(s)

references

government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA Integrated Risk Information System (IRIS)EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
European Commission on Endocrine DisruptionEU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
EPA Hazardous Air PollutantsEPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
National Library of Medicine HazMapNLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
Our Stolen Future Endocrine DisruptorsColborn T, D Dumanoski, JP Myers. 2006. Widespread Pollutants with Endocrine-disrupting Effects. Updated from original listing in "Our Stolen Future" (1996).
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.

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