Cancer |
Type of Concern |
Reference |
Known human carcinogen | Amer Conf of Gov't Industrial Hygienists - Carcinogens |
Known human carcinogen | EPA Integrated Risk Information System (IRIS) |
Known human carcinogen | Int'l Agency for Research on Cancer (IARC) - Carcinogens |
Known human carcinogen | NTP Report on Carcinogens, 11th Edition |
Known human carcinogen | European Union - Classification & Labelling |
Cancer - strong evidence | |
Cancer - strong evidence | CHE Toxicant and Disease Database |
Possible human carcinogen | NTP - Tumor Induction in Mammary Gland |
Possible human carcinogen | European Union - Classification & Labelling |
Limited evidence of carcinogenicity | NIOSH Occupational Carcinogens |
Cancer - moderate evidence - renal | CHE Toxicant and Disease Database |
show more |
Possible mutagen | European Union - Classification & Labelling |
One or more human case studies show possible cancer findings | NTP - Tumor Induction in Mammary Gland |
Cancer - limited evidence | CHE Toxicant and Disease Database |
Cancer - limited evidence | Silent Spring's Mammary Carcinogens Reviews Database | |
Developmental/reproductive toxicity |
Type of Concern |
Reference |
Possible human developmental toxicant | California EPA Proposition 65 |
Human developmental toxicant - strong evidence | |
Human reproductive toxicant - strong evidence | |
Limited evidence of reproductive toxicity | National Library of Medicine HazMap |
Human reproductive toxicant - moderate evidence | CHE Toxicant and Disease Database |
Human developmental toxicant - moderate evidence | CHE Toxicant and Disease Database |
Human nervous system toxicant - moderate evidence | Chemicals known to be neurotoxic to humans |
show more |
Limited evidence of cardiovascular toxicity | CHE Toxicant and Disease Database |
Limited evidence of nervous system toxicity | CHE Toxicant and Disease Database | |
references |
government/industry list/academic study
| reference
|
European Union - Classification & Labelling | CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP. |
Amer Conf of Gov't Industrial Hygienists - Carcinogens | ACGIH (American Conference of Governmental Industrial Hygienists) 2008. ACGIH cancer classification system. www.acgih.org. |
FDA Food Additive Status | FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006. |
Association of Occupational and Environmental Clinics | AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation. |
Canada - Prohibited and Restricted Cosmetics Ingredients | Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007. |
CHE Toxicant and Disease Database | CHE (The Collaborative on Health and the Environment). 2006. Toxicant and Disease Database. |
EPA Clean Water Act - Priority Pollutants | |
FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
EPA Integrated Risk Information System (IRIS) | EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines. |
European Union - Banned or Restricted in Cosmetics | EC (European Commission of the European Union). 1999-2006. Enterprise Directorate-General Pharmaceuticals and Cosmetics. The rules governing cosmetic products in the European Union, Volume 1, "Cosmetics legislation." |
European Union - Water Framework Directive | EU (European Union). 2000. Water Framework Directive (Directive 2000/60/EC ) - integrated river basin management for Europe. List of priority substances. |
EPA Hazardous Air Pollutants | EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005. |
National Library of Medicine HazMap | NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents. |
Int'l Agency for Research on Cancer (IARC) - Carcinogens | IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures). |
International Fragrance Association Codes & Standards | IFRA (International Fragrance Association). 2006. Codes and Standards. |
EPA Categorized List of Inert Pesticide Ingredients | EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients. |
Chemicals known to be neurotoxic to humans | Grandjean P and PJ Landrigan. 2006. Developmental neurotoxicity of industrial chemicals. Lancet. 2006 Dec 16;368(9553):2167-78. |
NIOSH Occupational Carcinogens | NIOSH (National Institute for Occupational Safety and Health). 2006. NIOSH Carcinogens List (Potential occupational carcinogens). http://www.cdc.gov/niosh/npotocca.html. |
NTP Report on Carcinogens, 11th Edition | NTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. |
NTP - Tumor Induction in Mammary Gland | NTP (National Toxicology Program) 2006. Chemicals Associated with Site-Specific Tumor Induction in Mammary Gland. |
EPA Toxic Release Inventory PBTs | EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule. |
California EPA Proposition 65 | California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity. |
Silent Spring's Mammary Carcinogens Reviews Database | Rudel RA, KR Attfield, JN Schifano and JG Brody. Chemicals Causing Mammary Gland Tumors in Animals Signal New Directions for Epidemiology, Chemicals Testing, and Risk Assessment for Breast Cancer Prevention. CANCER Supplement. 2007 Jun 15;109(12):2635-2666. |
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