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QUINOLINE


image source: PubChem
Health concerns of ingredient
About the ratings
Canceryes
Developmental & reproductive toxicity no information
Allergies & immunotoxicity no information
Other HIGH concerns: Organ system toxicity (non-reproductive), Multiple, additive exposure sources
Other MODERATE concerns: Persistence and bioaccumulation
Other LOW concerns: Ecotoxicology, Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Synonym(s): 1-AZANAPHTHALENE; B-500; 1-BENZAZINE; BENZO (B) PYRIDINE; CHINOLEINE; CHINOLIN (CZECH) ; CHINOLINE; LEUCOL; LEUKOL; USAF EK-218

Cancer

Type of Concern Reference
Known human carcinogenEPA Integrated Risk Information System (IRIS)
Possible human carcinogenEuropean Union - Classification & Labelling
Possible human carcinogenEPA Integrated Risk Information System (IRIS)
Possible carcinogenEnvironment Canada Domestic Substance List
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Organ system toxicity (non-reproductive)

Type of Concern Reference
Known human respiratory toxicantEPA Hazardous Air Pollutants
Classified as a high human health priorityEnvironment Canada Domestic Substance List
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
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Multiple, additive exposure sources

Type of Concern Reference
Used in food or as an additive with limited or no toxicity information available FDA Everything Added to Food

Persistence and bioaccumulation

Type of Concern Reference
Persistent or bioaccumulative and moderate to high toxicity concern in humansEnvironment Canada Domestic Substance List
Persistent, bioaccumulative in wildlifeCanada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
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Ecotoxicology

Type of Concern Reference
Wildlife and environmental toxicityEuropean Union - Classification & Labelling
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Data gaps

Type of Concern Reference
Not assessed for safety in cosmetics by industry panel

Government, industry, academic studies and classifications
government/industry list/academic study appears on list as classification(s)

references
government/industry list/academic study reference
European Union - Classification & LabellingCPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
FDA Everything Added to FoodFDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance ListEC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA Integrated Risk Information System (IRIS)EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
IFRA Fragrance Ingredient ListIFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
EPA Hazardous Air PollutantsEPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
EPA Toxic Release Inventory PBTsEPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.

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